GLP-1R modulator C16
Based on 1 Customer Validation
GLP-1R modulator C16 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 8.43 ± 3.82 μM).
For research use only. We do not sell to patients.
- Purity: 98.67%
- CAS No.: 875005-43-9
- Formula: C21H26ClFN2O3
- Molecular Weight:408.89
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 875005-43-9
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Appearance Solid
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Molecular Weight 408.89
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Formula C21H26ClFN2O3
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Color White to off-white
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SMILES
COC1=C(C=CC(CNCCN2CCOCC2)=C1)OCC3=C(C=CC=C3Cl)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (122.28 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4456 mL | 12.2282 mL | 24.4565 mL | 61.1411 mL |
| 5 mM | 0.4891 mL | 2.4456 mL | 4.8913 mL | 12.2282 mL | |
| 10 mM | 0.2446 mL | 1.2228 mL | 2.4456 mL | 6.1141 mL | |
| 15 mM | 0.1630 mL | 0.8152 mL | 1.6304 mL | 4.0761 mL | |
| 20 mM | 0.1223 mL | 0.6114 mL | 1.2228 mL | 3.0571 mL | |
| 25 mM | 0.0978 mL | 0.4891 mL | 0.9783 mL | 2.4456 mL | |
| 30 mM | 0.0815 mL | 0.4076 mL | 0.8152 mL | 2.0380 mL | |
| 40 mM | 0.0611 mL | 0.3057 mL | 0.6114 mL | 1.5285 mL | |
| 50 mM | 0.0489 mL | 0.2446 mL | 0.4891 mL | 1.2228 mL | |
| 60 mM | 0.0408 mL | 0.2038 mL | 0.4076 mL | 1.0190 mL | |
| 80 mM | 0.0306 mL | 0.1529 mL | 0.3057 mL | 0.7643 mL | |
| 100 mM | 0.0245 mL | 0.1223 mL | 0.2446 mL | 0.6114 mL |
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