2. GPCR/G Protein Neuronal Signaling
  3. CGRP Receptor
  4. Adrenomedullin (16-31), human

Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM). Adrenomedullin has appreciable affinity for the CGRP1 receptor. Adrenomedullin (16-31), human possesses pressor activity in the systemic vascular bed of the rat, but not the cat.

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Adrenomedullin (16-31), human Chemical Structure

Adrenomedullin (16-31), human Chemical Structure

CAS No. : 318480-38-5

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10 mg USD 420 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM). Adrenomedullin has appreciable affinity for the CGRP1 receptor. Adrenomedullin (16-31), human possesses pressor activity in the systemic vascular bed of the rat, but not the cat[1].

Molecular Weight

1865.19

Formula

C82H129N25O21S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-NH2
Sequence Shortening

CRFGTCTVQKLAHQIY-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (53.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5361 mL 2.6807 mL 5.3614 mL
5 mM 0.1072 mL 0.5361 mL 1.0723 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.5361 mL 2.6807 mL 5.3614 mL 13.4035 mL
5 mM 0.1072 mL 0.5361 mL 1.0723 mL 2.6807 mL
10 mM 0.0536 mL 0.2681 mL 0.5361 mL 1.3403 mL
15 mM 0.0357 mL 0.1787 mL 0.3574 mL 0.8936 mL
20 mM 0.0268 mL 0.1340 mL 0.2681 mL 0.6702 mL
25 mM 0.0214 mL 0.1072 mL 0.2145 mL 0.5361 mL
30 mM 0.0179 mL 0.0894 mL 0.1787 mL 0.4468 mL
40 mM 0.0134 mL 0.0670 mL 0.1340 mL 0.3351 mL
50 mM 0.0107 mL 0.0536 mL 0.1072 mL 0.2681 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Adrenomedullin (16-31), human Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adrenomedullin (16-31), human318480-38-5CGRP ReceptorCalcitonin gene-related peptide receptorInhibitorinhibitorinhibit

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