1. Anti-infection
  2. SARS-CoV
  3. SARS-CoV-2-IN-25

SARS-CoV-2-IN-25 

Cat. No.: HY-151267
Handling Instructions

SARS-CoV-2-IN-25 (Compound CP026) is a potent SARS-CoV-2 spike pseudoparticle transduction inhibitor with an IC50 of 1.6 μM. SARS-CoV-2-IN-25 inhibits enveloped viruses and liposomes.

For research use only. We do not sell to patients.

SARS-CoV-2-IN-25 Chemical Structure

SARS-CoV-2-IN-25 Chemical Structure

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Description

SARS-CoV-2-IN-25 (Compound CP026) is a potent SARS-CoV-2 spike pseudoparticle transduction inhibitor with an IC50 of 1.6 μM. SARS-CoV-2-IN-25 inhibits enveloped viruses and liposomes[1].

IC50 & Target

IC50: 1.5 μM (HIV-1), 1.6 μM (SARS-CoV-2 spike pseudoparticle transduction), 1.8 μM (SARS-CoV-2), 1.9 μM (MeV), 11.6 μM (IAV)[1]
EC50: 2.6 μM (liposome)[1]

In Vitro

SARS-CoV-2-IN-25 (Compound CP026) shows cytotoxicity with a CC50 of 117.9 μM against Caco2 cells[1].
SARS-CoV-2-IN-25 inhibits SARS-CoV-2, IAV, MeV, HIV-1 with IC50s of 1.8, 11.6, 1.9 and 1.5 μM, respectively. SARS-CoV-2-IN-25 inhibits liposome with an EC50 of 2.6 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

934.94

Formula

C58H48O8P2

SMILES

OP(OC1=C2C(C3C4=C(C2C3)C=C5C(C6C7=C(C5C6)C=CC=C7)=C4)=C(C8=C1C9C%10=CC(C%11CC%12C%13=C%11C=CC=C%13)=C%12C=C%10C8C9)OP(OCCC%14=CC=CC=C%14)(O)=O)(OCCC%15=CC=CC=C%15)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Product Name:
SARS-CoV-2-IN-25
Cat. No.:
HY-151267
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