1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Tubulin inhibitor 16

Tubulin inhibitor 16 is a potent tubulin inhibitor. Tubulin inhibitor 16 shows antiproliferative activity. Tubulin inhibitor 16 shows cytotoxicity in HepG2 cells.

For research use only. We do not sell to patients.

Tubulin inhibitor 16 Chemical Structure

Tubulin inhibitor 16 Chemical Structure

CAS No. : 2767446-32-0

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Description

Tubulin inhibitor 16 is a potent tubulin inhibitor. Tubulin inhibitor 16 shows antiproliferative activity. Tubulin inhibitor 16 shows cytotoxicity in HepG2 cells[1].

In Vitro

Tubulin inhibitor 16 (compound 2) (0-25 µM, 24 h followed by a 72 h compound-free incubation period) shows antiproliferative activity with IC50s of 1.43, 0.19, 2.33, 0.58, 0.83, 0.20, >25 µM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116, THLE-3 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116 cells
Concentration: 0-50 µM
Incubation Time: 96 h
Result: Showed antiproliferation activity with IC50s of 0.75, 0.17, 3.12, 0.41, 0.37, 0.22 µM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116 cells, respectively.

Cell Cytotoxicity Assay[1]

Cell Line: HepG2 cells
Concentration: 0.5, 1 µM
Incubation Time: 14 days
Result: Showed no colonies were apparent when cells were treated with 0.5 or 1 µM.
Molecular Weight

269.27

Formula

C16H12FNO2

CAS No.
SMILES

O=C1C2=CC=C(C=C2C=C(N1)C3=CC=CC(OC)=C3)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Tubulin inhibitor 16 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tubulin inhibitor 16
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HY-145822
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