2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. AT-121

AT-121 is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3.67 and 16.49 nM, respectively. AT-121 is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects.

For research use only. We do not sell to patients.

AT-121 Chemical Structure

AT-121 Chemical Structure

CAS No. : 2099681-31-7

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100 μg（2.16 mM * 100 μL in Chloroform） USD 148 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

AT-121 is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3.67 and 16.49 nM, respectively. AT-121 is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects[1].

In Vivo

AT-121 (0.003-0.03 mg/kg; s.c.) produces potent antinociceptive effect[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult male and female rhesus monkeys[1]
Dosage: 0.003-0.03 mg/kg
Administration: Subcutaneous
Result: Produced antinociceptive effects against an acute noxious stimulus, 50 °C water, in a dose-dependent.
Molecular Weight

462.65

Formula

C24H38N4O3S
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=S(N)(NCCN1CC2=C(C=CC=C2)C3(CCN([C@H]4CC[C@@H](C(C)C)CC4)CC3)C1=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Purity & Documentation

Purity: ≥96.0%

COA (253 KB)

Handling Instructions (2659 KB)
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AT-121 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AT-1212099681-31-7AT121AT 121Opioid Receptoranalgesicbifunctionalnonhumanprimatesantinociceptiveantiallodynicnon-addictivesafeInhibitorinhibitorinhibit

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