(S,R,S)-MI-1061
(S,R,S)-MI-1061 is the isomer of MI-1061(HY-125858). (S,R,S)-MI-1061 can used to synthesize Antibody-Drug Conjugates (ADCs). MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 1410738-90-7
- Formula: C30H26Cl2FN3O4
- Molecular Weight:582.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 1410738-90-7
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Molecular Weight 582.45
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Formula C30H26Cl2FN3O4
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SMILES
O=C1[C@@]2(C3=CC=C(Cl)C=C3N1)C4(CCCCC4)N[C@@H]([C@H]2C5=C(C(Cl)=CC=C5)F)C(NC6=CC=C(C=C6)C(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S,R,S)-MI-1061 Related Classifications
HY-125858B Related Classifications
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