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Sofituzumab

(Synonyms: MMUC 1206A)
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Based on 1 Customer Validation

Sofituzumab (MMUC 1206A) is an anti-MUC16 antibody with a Kd of 0.3-0.9 nM. Sofituzumab can bind multiple adjacent antibody molecules to the repeat sequences of the same MUC16 molecule. Sofituzumab exhibits no anti-tumor activity in the HPAC pancreatic adenocarcinoma xenograft model.

For research use only. We do not sell to patients.

  • Purity: 95.86%
  • CAS No.: 1615692-28-8
  • Molecular Weight:150 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Sofituzumab
  • Experimental Validation Results for Sofituzumab
  • Experimental Validation Results for Sofituzumab
  • Sofituzumab Chemical Structure
    Sofituzumab Chemical Structure
CAS No.: 1615692-28-8
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CA125 Protein, Human (HEK293, His, HY-P7696) can bind Sofituzumab. The EC50 for this effect is 8.646 ng/mL.

  • 1/16

    Flow Cytometry analysis of Hela cells labelling MUC16 (red) with Sofituzumab (anti-MUC16) (HY-P99237). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 (S228P) kappa (HY-P99003). Black-Unlabelled control, cells without incubation with primary antibody.

  • Sofituzumab Chemical Structure
    1/16
  • Sofituzumab
  • Immobilized CA125 Protein, Human (HEK293, His, HY-P7696) can bind Sofituzumab. The EC50 for this effect is 8.646 ng/mL.
  • Flow Cytometry analysis of Hela cells labelling MUC16 (red) with Sofituzumab (anti-MUC16) (HY-P99237). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 (S228P) kappa (HY-P99003). Black-Unlabelled control, cells without incubation with primary antibody.