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Cat. No.: HY-161061

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Arginase inhibitor 7

Arginase inhibitor 7 (compound A17) is an arginase (ARG1) inhibitor, with an IC₅₀ of 0.16 μM. Arginase inhibitor 7 has high oral bioavailability.

For research use only. We do not sell to patients.

CAS No.: 2377392-07-7
Formula: C₁₄H₂₉BN₆O₅
Molecular Weight:372.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Arginase inhibitor 7 Chemical Structure

CAS No.: 2377392-07-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Arginase inhibitor 7 (compound A17) is an arginase (ARG1) inhibitor, with an IC₅₀ of 0.16 μM. Arginase inhibitor 7 has high oral bioavailability^[1].

IC₅₀ & Target

IC50: 0.16 ± 0.03 μM (hARG1)^[1]

Chemical Information

CAS No. 2377392-07-7
Molecular Weight 372.23
Formula C₁₄H₂₉BN₆O₅
SMILES

NC(NCCC[C@@H](C(N1C[C@@H](CCB(O)O)C[C@](N)(C(O)=O)C1)=O)N)=N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gzik A, et al. Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion. Eur J Med Chem. 2023 Dec 10;264:116033. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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