PAR-4 (1-6) amide (human)

Name: PAR-4 (1-6) amide (human)
Brand: MedChemExpress
SKU: HY-P4004
Rating: 4.5 (1 reviews)

Cat. No.: HY-P4004 Purity: 98.82%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

PAR-4 (1-6) amide (human) Chemical Structure

CAS No. : 245443-51-0

Size	Price	Stock	Quantity
1 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation^[1].

In Vitro

PAR-4 (1-6) amide human (50, 100 µM) induces platelet aggregation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

618.68

Formula

C₂₈H₄₂N₈O₈

CAS No.

245443-51-0

Appearance

Solid

Color

White to off-white

Sequence Shortening

GYPGQV-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (161.63 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6163 mL	8.0817 mL	16.1634 mL
5 mM	0.3233 mL	1.6163 mL	3.2327 mL
10 mM	0.1616 mL	0.8082 mL	1.6163 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.82%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (254 KB) RP-HPLC (278 KB) MS (69 KB) Elemental Analysis Report (114 KB)

Handling Instructions (2659 KB)

References

[1]. Shimizu M, et al. Thrombin-induced platelet aggregation -effect of dabigatran using automated platelet aggregometry. Platelets. 2020;31(3):360-364. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.6163 mL	8.0817 mL	16.1634 mL	40.4086 mL
	5 mM	0.3233 mL	1.6163 mL	3.2327 mL	8.0817 mL
	10 mM	0.1616 mL	0.8082 mL	1.6163 mL	4.0409 mL
	15 mM	0.1078 mL	0.5388 mL	1.0776 mL	2.6939 mL
	20 mM	0.0808 mL	0.4041 mL	0.8082 mL	2.0204 mL
	25 mM	0.0647 mL	0.3233 mL	0.6465 mL	1.6163 mL
	30 mM	0.0539 mL	0.2694 mL	0.5388 mL	1.3470 mL
	40 mM	0.0404 mL	0.2020 mL	0.4041 mL	1.0102 mL
	50 mM	0.0323 mL	0.1616 mL	0.3233 mL	0.8082 mL
	60 mM	0.0269 mL	0.1347 mL	0.2694 mL	0.6735 mL
	80 mM	0.0202 mL	0.1010 mL	0.2020 mL	0.5051 mL
	100 mM	0.0162 mL	0.0808 mL	0.1616 mL	0.4041 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PAR-4 (1-6) amide (human)245443-51-0OthersInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name			Lot #
Applicant Name *			Email Address *
Phone Number			Department *
Organization Name *			Country or Region *
Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

PAR-4 (1-6) amide (human)

Customer Review