MUC16 Antibody (YA3530)
MUC16 Antibody (YA3530) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MUC16.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P
-
Reactivity :
Human
-
Formulation:
Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 |
Product Details
MUC16 Antibody (YA3530) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MUC16.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 90-100 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 1519 kDa
A synthesized peptide derived from human CA-125 (MUC16) aa12260-12320.
Endogenous
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Background
-
Function
MUC16 is a Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces
-
Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Secreted, extracellular space
-
Expression
Tissue_specificity:It is expressed in corneal and conjunctival epithelial cells (protein level) . Compared with normal ovarian tissue and ovarian adenoma, it is overexpressed in ovarian cancer and low-grade malignant potential (LMP) ovarian tumors.
Induction:Up-regulated in ovarian cancer cells -
Subunit
Binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN
-
SwissProt ID
-
Research Field
Cancer
Documentation
Powered by Bioz
