MUC16 Antibody (YA3530)

Cat. No.: HY-P80991: Ficha de datos User Guide for Antibodies
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Technical Support

MUC16 Antibody (YA3530) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MUC16.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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MUC16 Antibody (YA3530) Recomendaciones destacadas:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

MUC16 Antibody (YA3530) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MUC16.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Peso molecular

Predicted band size: 1519 kDa;

Observed band size: 90-100 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q8WXI7

Gene ID

94025 [NCBI]

Immunogen

A synthesized peptide derived from human CA-125 (MUC16) aa12260-12320.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100

Sensitivity	Endogenous	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Background

Function：Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces

Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Secreted, extracellular space

Expression：
Tissue_specificity:It is expressed in corneal and conjunctival epithelial cells (protein level) . Compared with normal ovarian tissue and ovarian adenoma, it is overexpressed in ovarian cancer and low-grade malignant potential (LMP) ovarian tumors.

Induction:Up-regulated in ovarian cancer cells

Subunit：Binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN

Database

Entrez Gene: 94025 Human

SwissProt: Q8WXI7 Human

OMIM: 606154 Human

Research Field

Cancer

Documentación

User Guide for Antibodies (1077 KB)

MUC16 Antibody (YA3530) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MUC16 Antibody (YA3530)

MUC16 Antibody (YA3530) Recomendaciones destacadas:

Product Detail

Background

Descripciòn

MUC16 Antibody (YA3530) Related Classifications

Productos vistos recientemente:

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