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  4. Palmitoleoyl 3-carbacyclic phosphatidic acid

Palmitoleoyl 3-carbacyclic phosphatidic acid 

Cat. No.: HY-134954
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Palmitoleoyl 3-carbacyclic phosphatidic acid (3ccPA 16:1) is an intermediately potent inhibitor of autotaxin (ATX) with an IC50 of 620 nM. Palmitoleoyl 3-carbacyclic phosphatidic acid can be used for melanoma research.

For research use only. We do not sell to patients.

Palmitoleoyl 3-carbacyclic phosphatidic acid Chemical Structure

Palmitoleoyl 3-carbacyclic phosphatidic acid Chemical Structure

CAS No. : 910228-13-6

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Palmitoleoyl 3-carbacyclic phosphatidic acid Related Antibodies

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Description

Palmitoleoyl 3-carbacyclic phosphatidic acid (3ccPA 16:1) is an intermediately potent inhibitor of autotaxin (ATX) with an IC50 of 620 nM. Palmitoleoyl 3-carbacyclic phosphatidic acid can be used for melanoma research[1].

IC50 & Target

IC50: 620 nM (Autotaxin) [1]
In Vitro

Palmitoleoyl 3-carbacyclic phosphatidic acid (3 μM, 22 h) significantly attenuated (81%) the ATX- and LPC-induced invasion of A2058 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Palmitoleoyl 3-carbacyclic phosphatidic acid Related Antibodies
In Vivo

Palmitoleoyl 3-carbacyclic phosphatidic acid (250 μg/kg, i.p., 15 min and 48 h after the i.v. of 5 × 105 B16F10 melanoma cells per mouse) blocks 1/3 of the lung metastasis of melanoma cells (37±10 tumors) compared with vehicle control (57±14 tumors)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

388.48

Formula

C20H37O5P
CAS No.
SMILES

CCCCCC/C=C\CCCCCCCC(OCC1OP(O)(CC1)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Palmitoleoyl 3-carbacyclic phosphatidic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Palmitoleoyl 3-carbacyclic phosphatidic acid910228-13-6OthersautotaxininhibitormelanomaLPCA2058B16F10Inhibitorinhibit

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