1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. VEGFR-2-IN-16

VEGFR-2-IN-16 

Cat. No.: HY-144803
Handling Instructions

VEGFR-2-IN-16 (Compound 15b) is a potent VEGFR-2 inhibitor with an IC50 of 86.36 nM. VEGFR-2-IN-16 shows antitumor activities.

For research use only. We do not sell to patients.

VEGFR-2-IN-16 Chemical Structure

VEGFR-2-IN-16 Chemical Structure

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Description

VEGFR-2-IN-16 (Compound 15b) is a potent VEGFR-2 inhibitor with an IC50 of 86.36 nM. VEGFR-2-IN-16 shows antitumor activities[1].

IC50 & Target

VEGFR2

86.36 nM (IC50)

In Vitro

VEGFR-2-IN-16 (Compound 15b) shows antiproliferative activities with IC50 values of 17.39 ± 1.54, 25.58 ± 2.31, 19.88 ± 1.79 and 233.21 ± 2.39 µM against HepG2, PC3, MCF-7 and WI-38 cells, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

410.25

Formula

C21H13Cl2N3O2

SMILES

O=C(NC1=CC=C(OC2=C3C=CC=CC3=NC(Cl)=N2)C=C1)C4=CC=C(Cl)C=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
VEGFR-2-IN-16
Cat. No.:
HY-144803
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