ADRA1D receptor antagonist 1
Based on 1 Customer Validation
ADRA1D receptor antagonist 1 is a potent, selective and orally active α1D adrenoceptor antagonist, with a Ki of 1.6 nM.
For research use only. We do not sell to patients.
- Purity: 98.03%
- CAS No.: 1191908-14-1
- Formula: C15H14Cl2N4O
- Molecular Weight:337.20
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Ki: 1.6 nM (α1D adrenoceptor)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rat with bladder outlet obstruction (BOO)[1]
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Dosage:4.4 µg/kg
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Administration:Intravenous injection
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Result:Dose-dependently decreased the non-voiding bladder contractions during urinary storage phase in rats with BOO.
Chemical Information
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CAS No. 1191908-14-1
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Appearance Solid
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Molecular Weight 337.20
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Formula C15H14Cl2N4O
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Color Yellow to brown
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SMILES
O=C(C1=CC(Cl)=CN([C@@H](C2=CC=CC(C#N)=C2)C)C1=N)N.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (296.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9656 mL | 14.8280 mL | 29.6560 mL | 74.1400 mL |
| 5 mM | 0.5931 mL | 2.9656 mL | 5.9312 mL | 14.8280 mL | |
| 10 mM | 0.2966 mL | 1.4828 mL | 2.9656 mL | 7.4140 mL | |
| 15 mM | 0.1977 mL | 0.9885 mL | 1.9771 mL | 4.9427 mL | |
| 20 mM | 0.1483 mL | 0.7414 mL | 1.4828 mL | 3.7070 mL | |
| 25 mM | 0.1186 mL | 0.5931 mL | 1.1862 mL | 2.9656 mL | |
| 30 mM | 0.0989 mL | 0.4943 mL | 0.9885 mL | 2.4713 mL | |
| 40 mM | 0.0741 mL | 0.3707 mL | 0.7414 mL | 1.8535 mL | |
| 50 mM | 0.0593 mL | 0.2966 mL | 0.5931 mL | 1.4828 mL | |
| 60 mM | 0.0494 mL | 0.2471 mL | 0.4943 mL | 1.2357 mL | |
| 80 mM | 0.0371 mL | 0.1853 mL | 0.3707 mL | 0.9267 mL | |
| 100 mM | 0.0297 mL | 0.1483 mL | 0.2966 mL | 0.7414 mL |
ADRA1D receptor antagonist 1 Related Classifications
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