1. Apoptosis
  2. Apoptosis
  3. Kauran-16,17-diol

Kauran-16,17-diol  (Synonyms: ent-Kauran-16β,17-diol)

Cat. No.: HY-N7422 Purity: 99.51%
COA Handling Instructions

Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages.

For research use only. We do not sell to patients.

Kauran-16,17-diol Chemical Structure

Kauran-16,17-diol Chemical Structure

CAS No. : 16836-31-0

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5 mg USD 540 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[1][2].

In Vitro

Kauran-16,17-diol (ent-Kauran-16β,17-diol) down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

306.48

Formula

C20H34O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]1(CCC2)[C@@]3([H])[C@](C[C@H]4CC3)(CC[C@]1([H])C2(C)C)C[C@]4(O)CO

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Kauran-16,17-diol Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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