1. Protein Tyrosine Kinase/RTK
  2. Btk

Fenebrutinib (Synonyms: GDC-0853)

Cat. No.: HY-19834 Purity: 99.50%
Handling Instructions

Fenebrutinib (GDC-0853) is a potent, selective, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with a Ki of 0.91 nM.

For research use only. We do not sell to patients.

Fenebrutinib Chemical Structure

Fenebrutinib Chemical Structure

CAS No. : 1434048-34-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 139 In-stock
Estimated Time of Arrival: December 31
2 mg USD 60 In-stock
Estimated Time of Arrival: December 31
5 mg USD 95 In-stock
Estimated Time of Arrival: December 31
10 mg USD 170 In-stock
Estimated Time of Arrival: December 31
25 mg USD 380 In-stock
Estimated Time of Arrival: December 31
50 mg USD 680 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1150 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Fenebrutinib (GDC-0853) is a potent, selective, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with a Ki of 0.91 nM.

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 23 mg/mL (34.60 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5042 mL 7.5211 mL 15.0421 mL
5 mM 0.3008 mL 1.5042 mL 3.0084 mL
10 mM 0.1504 mL 0.7521 mL 1.5042 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

664.80

Formula

C₃₇H₄₄N₈O₄

CAS No.

1434048-34-6

SMILES

O=C1C(NC(C=C2)=NC=C2N3CCN(C4COC4)C[[email protected]@H]3C)=CC(C5=CC=NC(N6C(C7=CC(CC(C)(C)C8)=C8N7CC6)=O)=C5CO)=CN1C

Storage

4°C, stored under nitrogen

Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.50%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Fenebrutinib
Cat. No.:
HY-19834
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Fenebrutinib

Cat. No.: HY-19834