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P-gp/BCRP-IN-2

P-gp/BCRP-IN-2 (compound 15) is an oxadiazole derivative and a dual inhibitor of the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP (IC50: 600 nM). P-gp/BCRP-IN-2 also enhances the anti-proliferative effects of Doxorubicin (HY-15142A) in drug-resistant human adenocarcinoma colon cancer cell lines HT29/DX and MDCK-MDR1 cells.

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  • CAS No.: 3052839-42-3
  • Formula: C32H35N3O6
  • Molecular Weight:557.64
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • P-gp/BCRP-IN-2 Chemical Structure
    P-gp/BCRP-IN-2 Chemical Structure
CAS No.: 3052839-42-3
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  • P-gp/BCRP-IN-2 Chemical Structure
    P-gp/BCRP-IN-2 Chemical Structure
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  • P-gp/BCRP-IN-2