1. Protein Tyrosine Kinase/RTK
  2. FGFR
    VEGFR
  3. ODM-203

ODM-203 

Cat. No.: HY-119367
Handling Instructions

ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. ODM-203 exhibits strong anti-tumor activity and induces anti-tumor immunity.

For research use only. We do not sell to patients.

ODM-203 Chemical Structure

ODM-203 Chemical Structure

CAS No. : 1430723-35-5

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products

View All FGFR Isoform Specific Products:

View All VEGFR Isoform Specific Products:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. ODM-203 exhibits strong anti-tumor activity and induces anti-tumor immunity[1].

IC50 & Target[1]

FGFR1

11 nM (IC50)

FGFR2

16 nM (IC50)

FGFR3

6 nM (IC50)

FGFR4

35 nM (IC50)

VEGFR1

26 nM (IC50)

VEGFR2

9 nM (IC50)

VEGFR3

5 nM (IC50)

DDR1

6 nM (IC50)

RET

8 nM (IC50)

SIK3

23 nM (IC50)

PDGFRa

35 nM (IC50)

MINK1

41 nM (IC50)

MAP4K4

49 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

505.54

Formula

C₂₆H₂₁F₂N₅O₂S

CAS No.

1430723-35-5

SMILES

CN(N=C1)C=C1C2=CC=C3C(N=CN3C4=CC(C5=CC=C(F)C=C5F)=CC(NS(C6CC6)(=O)=O)=C4)=C2

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
ODM-203
Cat. No.:
HY-119367
Quantity:

ODM-203

Cat. No.: HY-119367