1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

Adrenic Acid (Synonyms: cis-7,10,13,16-Docosatetraenoic acid)

Cat. No.: HY-W013215
Handling Instructions

Adrenic Acid is an inflammation enhancer in non-alcoholic fatty liver disease.

For research use only. We do not sell to patients.

Adrenic Acid Chemical Structure

Adrenic Acid Chemical Structure

CAS No. : 28874-58-0

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References


Adrenic Acid is an inflammation enhancer in non-alcoholic fatty liver disease.

IC50 & Target

Human Endogenous Metabolite


In Vitro

Adrenic acid is produced via the elongation of arachidonic acid by ELOVL2 and 5. Interestingly, the hepatic level of free Adrenic Acid (22:4n6) is markedly higher in the CDAHFD-fed db/db mice than in the SD-fed db/db mice. In plasma, the difference in the adrenic acid level reaches statistical significance (p<0.001). It is also found that the concentrations of phospholipid species containing Adrenic Acid, such as PC or PE (40:4) (containing side chain 18:0/22:4), and LPC 22:4 (sn-1/sn-2), are also significantly increased. (sn-1/sn-2). The hepatic and plasma levels of Adrenic Acid, which is an omega 6 polyunsaturated fatty acid (PUFA), exhibit greater differences between the CDAHFD-fed db/db mice and the SD-fed db/db mice (8.6-fold higher vs. 1.6-fold higher in liver tissue, 5.3-fold higher vs. 2.2-fold higher in plasma) than those of well-known proinflammatory PUFA, such as Arachidonic Acid[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0072 mL 15.0362 mL 30.0725 mL
5 mM 0.6014 mL 3.0072 mL 6.0145 mL
10 mM 0.3007 mL 1.5036 mL 3.0072 mL
*Please refer to the solubility information to select the appropriate solvent.
Molecular Weight









Please store the product under the recommended conditions in the Certificate of Analysis.


Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Adrenic Acid
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Adrenic Acid

Cat. No.: HY-W013215