Steroid sulfatase-IN-4
Steroid sulfatase-IN-4 (Compound 16) is an irreversible steroid sulfatase (STS) inhibitor with an IC50 of 25 nM against human STS. Steroid sulfatase-IN-4 can be used for the research of endometriosis.
For research use only. We do not sell to patients.
- CAS No.: 2990549-73-8
- Formula: C19H17ClN2O5S
- Molecular Weight:420.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 25 nM (hSTS in cellular assays)[1]
Steroid sulfatase-IN-4 (Compound 16) shows good metabolic stability in human hepatic S9 fraction and low intrinsic clearance Clint (<30 μL/min/mg protein)[1].
Steroid sulfatase-IN-4 (20 μM; 24 h) shows cytotoxicity for HEK-293 cells (53.6% inhibition)[1].
Steroid sulfatase-IN-4 (1 μM) shows 25% inhibition against human 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) in a cell-free assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2990549-73-8
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Molecular Weight 420.87
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Formula C19H17ClN2O5S
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SMILES
O=S(OC1=CC=C(C2=CC=C(C(N(C)C3=CC=CC=C3C)=O)O2)C=C1Cl)(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Steroid sulfatase-IN-4 Related Classifications
HY-151200 Related Classifications
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