Hongotoxin-1
Hongotoxin-1, isolated from venom of Centruroides limbatus, is the inhibitor of potassium channel, with IC50 for? Kv1.1, Kv1.2, Kv1.3, and Kv1.6 of 31 pM, 170 pM, 86 pM,and 6000 pM, respectively.
For research use only. We do not sell to patients.
- Formula: C181H299N53O49S7
- Molecular Weight:4226.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Kv1.1 31 pM (IC50) |
Kv1.2 170 pM (IC50) |
Kv1.3 86 pM (IC50) |
Kv1.6 6000 pM (IC50) |
Chemical Information
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Molecular Weight 4226.13
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Formula C181H299N53O49S7
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Sequence
Thr-Val-Ile-Asp-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Ile-Arg-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His (Disulfide bridge:Cys3-Cys17;Cys10-Cys21;Cys16-Cys32)
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Sequence Shortening
TVIDVKCTSPKQCLPPCKAQFGIRAGAKCMNGKCKCYPH (Disulfide bridge:Cys3-Cys17;Cys10-Cys21;Cys16-Cys32)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)