1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin
  3. Estramustine

Estramustine 

Cat. No.: HY-103711
Handling Instructions

Estramustine is an antineoplastic agent. Estramustine depolymerizes microtnbules by binding to tubulin 1, exhibits antimitotic activity with an IC50 value of ~16 μM for mitosis of DU 145 cells. Estramustine blocks cells at mitosis in prostate tumor xenografts.

For research use only. We do not sell to patients.

Estramustine Chemical Structure

Estramustine Chemical Structure

CAS No. : 2998-57-4

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Description

Estramustine is an antineoplastic agent. Estramustine depolymerizes microtnbules by binding to tubulin 1, exhibits antimitotic activity with an IC50 value of ~16 μM for mitosis of DU 145 cells. Estramustine blocks cells at mitosis in prostate tumor xenografts[1].

IC50 & Target

Tubulin 1[1]

Molecular Weight

440.40

Formula

C23H31Cl2NO3

CAS No.
SMILES

C[[email protected]@]12[[email protected]](CC[[email protected]@H]2O)([H])[[email protected]@]3([H])[[email protected]@](CC1)([H])C4=CC=C(OC(N(CCCl)CCCl)=O)C=C4CC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Estramustine
Cat. No.:
HY-103711
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