Pomalidomide 4'-alkylC4-acid

Cat. No.: HY-131886 Purity: 98.04%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Pomalidomide 4'-alkylC4-acid (linker16) is a E3 Ligase Ligand-Linker Conjugate. Pomalidomide 4'-alkylC4-acid can be used for conjugation to a target protein ligand.

For research use only. We do not sell to patients.

Pomalidomide 4'-alkylC4-acid Chemical Structure

CAS No. : 2225940-48-5

Size	Price	Stock	Quantity
5 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Pomalidomide 4'-alkylC4-acid (linker16) is a E3 Ligase Ligand-Linker Conjugate. Pomalidomide 4'-alkylC4-acid can be used for conjugation to a target protein ligand^[1].

Molecular Weight

373.36

Formula

C₁₈H₁₉N₃O₆

CAS No.

2225940-48-5

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(CCCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (334.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6784 mL	13.3919 mL	26.7838 mL
5 mM	0.5357 mL	2.6784 mL	5.3568 mL
10 mM	0.2678 mL	1.3392 mL	2.6784 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.04%

Select Batch:

Data Sheet (273 KB) SDS (0 KB)

COA (255 KB) HNMR (287 KB) LCMS (90 KB)

Handling Instructions (2659 KB)

References

[1]. Michael Bruno Plewe, et al. Compounds and methods of treating cancers. China CN202080026538.3A. 2020-04-02

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6784 mL	13.3919 mL	26.7838 mL	66.9595 mL
	5 mM	0.5357 mL	2.6784 mL	5.3568 mL	13.3919 mL
	10 mM	0.2678 mL	1.3392 mL	2.6784 mL	6.6960 mL
	15 mM	0.1786 mL	0.8928 mL	1.7856 mL	4.4640 mL
	20 mM	0.1339 mL	0.6696 mL	1.3392 mL	3.3480 mL
	25 mM	0.1071 mL	0.5357 mL	1.0714 mL	2.6784 mL
	30 mM	0.0893 mL	0.4464 mL	0.8928 mL	2.2320 mL
	40 mM	0.0670 mL	0.3348 mL	0.6696 mL	1.6740 mL
	50 mM	0.0536 mL	0.2678 mL	0.5357 mL	1.3392 mL
	60 mM	0.0446 mL	0.2232 mL	0.4464 mL	1.1160 mL
	80 mM	0.0335 mL	0.1674 mL	0.3348 mL	0.8370 mL
	100 mM	0.0268 mL	0.1339 mL	0.2678 mL	0.6696 mL