1. Others Immunology/Inflammation
  2. Others Toll-like Receptor (TLR)
  3. Ergosta-7,22-dien-3-one

Ergosta-7,22-dien-3-on is a lanosterane isolated from the fruiting bodies of Ganoderma lucidum. ent-16-Kaurene-3b,15b,18-triol inhibits platelet aggregation. Ergosta-7,22-dien-3-on is able to stimulate nitric oxide production, induce the expression of genes, and induce the production of TLRs, cytokines, chemokines, and cellular adhesion molecules in vitro.

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Ergosta-7,22-dien-3-one

Ergosta-7,22-dien-3-one Chemical Structure

CAS No. : 32507-77-0

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Description

Ergosta-7,22-dien-3-on is a lanosterane isolated from the fruiting bodies of Ganoderma lucidum. ent-16-Kaurene-3b,15b,18-triol inhibits platelet aggregation[1][2]. Ergosta-7,22-dien-3-on is able to stimulate nitric oxide production, induce the expression of genes, and induce the production of TLRs, cytokines, chemokines, and cellular adhesion molecules in vitro[3].

Molecular Weight

396.65

Formula

C28H44O

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)/C=C/[C@H](C)C(C)C)([H])C3=CCC(CC(CC4)=O)[C@@]4(C)[C@@]3([H])CC1

Structure Classification
Initial Source

Ganoderma mastoporum

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ergosta-7,22-dien-3-one
Cat. No.:
HY-N3844
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