1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor
  3. KNT-127

KNT-127 

Cat. No.: HY-120511
Handling Instructions

KNT-127 is a potent and selective δ-opioid receptor agonist effective by systemic administration. KNT-127 shows selectivity for the δ-receptor (Ki 0f 21.3, 0.16, 153 nM for opioid μ-, δ-, and κ-receptors, respectively). KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex. Antidepressant-like effects.

For research use only. We do not sell to patients.

KNT-127 Chemical Structure

KNT-127 Chemical Structure

CAS No. : 1256921-89-7

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Description

KNT-127 is a potent and selective δ-opioid receptor agonist effective by systemic administration. KNT-127 shows selectivity for the δ-receptor (Ki 0f 21.3, 0.16, 153 nM for opioid μ-, δ-, and κ-receptors, respectively). KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex. Antidepressant-like effects[1][2].

Molecular Weight

372.46

Formula

C24H24N2O2

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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KNT-127
Cat. No.:
HY-120511
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