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FAK-IN-16

FAK-IN-16 (compound OXA-11) is an orally active, selective focal adhesion kinase (FAK) inhibitor with an IC50 of 1.2 pM. FAK-IN-16 inhibits FAK phosphorylation at pFAK[Y397] and pFAK[Y861]. FAK-IN-16 slows tumor growth and reduces tumor vascularity, invasion. FAK-IN-16 potentiates effects of Cisplatin (HY-17394) on tumor cell proliferation and apoptosis in vitro and anti-tumor actions in mice.

For research use only. We do not sell to patients.

  • CAS No.: 1257994-15-2
  • Formula: C37H49F3N7O5P
  • Molecular Weight:759.80
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FAK-IN-16 Chemical Structure
    FAK-IN-16 Chemical Structure
CAS No.: 1257994-15-2
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  • FAK-IN-16 Chemical Structure
    FAK-IN-16 Chemical Structure
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  • FAK-IN-16