Dibenzylideneacetone
Based on 1 Customer Validation
Dibenzylideneacetone (Dibenzalacetone) is a potent inhibitor of chitinase with an IC50 value of 13.10 μM. The MIC value of Dibenzylideneacetone against Botrytis cinerea is 32 μg/mL, and the EC50 values for inhibiting mycelium growth and spore germination are 16.29 and 14.64 μg/mL, respectively. Dibenzylideneacetone can be used in research on fruit and vegetable preservatives.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.86%
- CAS. Nr.: 538-58-9
- Formel: C17H14O
- Molecular Weight:234.30
-
Speicherung:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
-
Lösungsmittel & Löslichkeit
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | IC50 |
0.053 nM
Compound: 2a
|
Inhibition of tissue factor in Homo sapiens (human) THP1-cells using factor 10a chromogenic substrate assessed as inhibition of LPS-iduced procoagulant activity incubated for 1 hr prior to LPS-challenge measured after 5 hr by spectrophotometric analysis
Inhibition of tissue factor in Homo sapiens (human) THP1-cells using factor 10a chromogenic substrate assessed as inhibition of LPS-iduced procoagulant activity incubated for 1 hr prior to LPS-challenge measured after 5 hr by spectrophotometric analysis
|
10.1007/s00044-012-0330-5 |
Chemical Information
-
CAS. Nr. 538-58-9
-
Appearance Solid
-
Molecular Weight 234.30
-
Formel C17H14O
-
Color Light yellow to yellow
-
SMILES
O=C(/C=C/C1=CC=CC=C1)/C=C/C2=CC=CC=C2
-
Synonyms
Dibenzalacetone
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (426.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Protokoll
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
-
Data Sheet (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Verweise
[1]. Niu X, Wang Z, Wang C, Wang H. Dibenzylideneacetone Overcomes Botrytis cinerea Infection in Cherry Tomatoes by Inhibiting Chitinase Activity. J Agric Food Chem. 2023 Nov 1. [Content Brief]
[2]. Niu X, et al. Dibenzylideneacetone Overcomes Botrytis cinerea Infection in Cherry Tomatoes by Inhibiting Chitinase Activity. J Agric Food Chem. 2023 Nov 1. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2680 mL | 21.3402 mL | 42.6803 mL | 106.7008 mL |
| 5 mM | 0.8536 mL | 4.2680 mL | 8.5361 mL | 21.3402 mL | |
| 10 mM | 0.4268 mL | 2.1340 mL | 4.2680 mL | 10.6701 mL | |
| 15 mM | 0.2845 mL | 1.4227 mL | 2.8454 mL | 7.1134 mL | |
| 20 mM | 0.2134 mL | 1.0670 mL | 2.1340 mL | 5.3350 mL | |
| 25 mM | 0.1707 mL | 0.8536 mL | 1.7072 mL | 4.2680 mL | |
| 30 mM | 0.1423 mL | 0.7113 mL | 1.4227 mL | 3.5567 mL | |
| 40 mM | 0.1067 mL | 0.5335 mL | 1.0670 mL | 2.6675 mL | |
| 50 mM | 0.0854 mL | 0.4268 mL | 0.8536 mL | 2.1340 mL | |
| 60 mM | 0.0711 mL | 0.3557 mL | 0.7113 mL | 1.7783 mL | |
| 80 mM | 0.0534 mL | 0.2668 mL | 0.5335 mL | 1.3338 mL | |
| 100 mM | 0.0427 mL | 0.2134 mL | 0.4268 mL | 1.0670 mL |
Dibenzylideneacetone Related Classifications
HY-75828 Related Classifications
Powered by Bioz