1. Metabolic Enzyme/Protease
  2. FBPase
  3. FBPase-1 inhibitor-1

FBPase-1 inhibitor-1 (compound 1) is a allosteric inhibitor of fructose-1,6-bisphosphatase (FBPase-1).

For research use only. We do not sell to patients.

FBPase-1 inhibitor-1 Chemical Structure

FBPase-1 inhibitor-1 Chemical Structure

CAS No. : 883973-99-7

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Based on 1 publication(s) in Google Scholar

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Description

FBPase-1 inhibitor-1 (compound 1) is a allosteric inhibitor of fructose-1,6-bisphosphatase (FBPase-1)[1].

Molecular Weight

377.63

Formula

C13H7Cl3N2O3S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC(Cl)=CC=C1Cl)(NC2=NC3=CC(Cl)=CC=C3O2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (331.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6481 mL 13.2405 mL 26.4809 mL
5 mM 0.5296 mL 2.6481 mL 5.2962 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6481 mL 13.2405 mL 26.4809 mL 66.2024 mL
5 mM 0.5296 mL 2.6481 mL 5.2962 mL 13.2405 mL
10 mM 0.2648 mL 1.3240 mL 2.6481 mL 6.6202 mL
15 mM 0.1765 mL 0.8827 mL 1.7654 mL 4.4135 mL
20 mM 0.1324 mL 0.6620 mL 1.3240 mL 3.3101 mL
25 mM 0.1059 mL 0.5296 mL 1.0592 mL 2.6481 mL
30 mM 0.0883 mL 0.4413 mL 0.8827 mL 2.2067 mL
40 mM 0.0662 mL 0.3310 mL 0.6620 mL 1.6551 mL
50 mM 0.0530 mL 0.2648 mL 0.5296 mL 1.3240 mL
60 mM 0.0441 mL 0.2207 mL 0.4413 mL 1.1034 mL
80 mM 0.0331 mL 0.1655 mL 0.3310 mL 0.8275 mL
100 mM 0.0265 mL 0.1324 mL 0.2648 mL 0.6620 mL
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FBPase-1 inhibitor-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FBPase-1 inhibitor-1
Cat. No.:
HY-136717
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