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Cat. No.: HY-117708

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Antitumor agent-144

Antitumor agent-144 (16) is an antitumor agent, with IC₅₀ values of 2.6 μM and 8.4 μM in L1210 and KB cells, respectively.

For research use only. We do not sell to patients.

CAS No.: 137346-42-0
Formula: C₂₅H₂₆N₄O₄
Molecular Weight:446.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antitumor agent-144 Chemical Structure

CAS No.: 137346-42-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Antitumor agent-144 (16) is an antitumor agent, with IC₅₀ values of 2.6 μM and 8.4 μM in L1210 and KB cells, respectively^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
KB	IC₅₀	7.6 μM Compound: 17	In vitro antitumor activity against human epidermoid carcinoma KB cells by MTT assay. In vitro antitumor activity against human epidermoid carcinoma KB cells by MTT assay.	10.1016/0960-894X(95)00353-U
L1210	IC₅₀	9.6 μM Compound: 17	In vitro antitumor activity against murine lymphoma L1210 cells by MTT assay. In vitro antitumor activity against murine lymphoma L1210 cells by MTT assay.	10.1016/0960-894X(95)00353-U
V79	IC₅₀	19 μM Compound: 13	Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under anaerobic conditions Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under anaerobic conditions	10.1016/0960-894X(95)00352-T
V79	IC₅₀	27 μM Compound: 13	Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under aerobic conditions Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under aerobic conditions	10.1016/0960-894X(95)00352-T

Chemical Information

CAS No. 137346-42-0
Molecular Weight 446.50
Formula C₂₅H₂₆N₄O₄
SMILES

O=C1C2=CC3=C(N(C2=NC(N1C4=CC=CC=C4)=O)CCCCCCCC)C=CC([N+]([O-])=O)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tetsuji Kawamoto, et al. Synthesis and evaluation of nitro 5-deazaflavins as novel bioreductive antitumor agents. Bioorganic & Medicinal Chemistry Letters. Volume 5, Issue 18, 21 September 1995, Pages 2109-2114.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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