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製品番号: HY-117708

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Antitumor agent-144

Name: Antitumor agent-144
Brand: MedChemExpress
SKU: HY-117708
Price: 319.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Antitumor agent-144 (16) is an antitumor agent, with IC₅₀ values of 2.6 μM and 8.4 μM in L1210 and KB cells, respectively.

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CAS 番号: 137346-42-0
分子式: C₂₅H₂₆N₄O₄
分子量:446.50

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antitumor agent-144 構造式

CAS 番号: 137346-42-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Antitumor agent-144 (16) is an antitumor agent, with IC₅₀ values of 2.6 μM and 8.4 μM in L1210 and KB cells, respectively^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
KB	IC₅₀	7.6 μM Compound: 17	In vitro antitumor activity against human epidermoid carcinoma KB cells by MTT assay. In vitro antitumor activity against human epidermoid carcinoma KB cells by MTT assay.	10.1016/0960-894X(95)00353-U
L1210	IC₅₀	9.6 μM Compound: 17	In vitro antitumor activity against murine lymphoma L1210 cells by MTT assay. In vitro antitumor activity against murine lymphoma L1210 cells by MTT assay.	10.1016/0960-894X(95)00353-U
V79	IC₅₀	19 μM Compound: 13	Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under anaerobic conditions Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under anaerobic conditions	10.1016/0960-894X(95)00352-T
V79	IC₅₀	27 μM Compound: 13	Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under aerobic conditions Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under aerobic conditions	10.1016/0960-894X(95)00352-T

化学情報

CAS 番号 137346-42-0
分子量 446.50
分子式 C₂₅H₂₆N₄O₄
SMILES

O=C1C2=CC3=C(N(C2=NC(N1C4=CC=CC=C4)=O)CCCCCCCC)C=CC([N+]([O-])=O)=C3
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Tetsuji Kawamoto, et al. Synthesis and evaluation of nitro 5-deazaflavins as novel bioreductive antitumor agents. Bioorganic & Medicinal Chemistry Letters. Volume 5, Issue 18, 21 September 1995, Pages 2109-2114.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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