2. Neuronal Signaling
  3. Sigma Receptor
  4. NE-100 hydrochloride

NE-100 hydrochloride 

Cat. No.: HY-101484A Purity: 98.90%
COA Handling Instructions

NE-100 (hydrochloride) is a potent and selective sigma-1 receptor antagonist with an IC50 of 4.16 nM. NE-100 (hydrochloride) exerts antipsychotic activity in vivo[1]. NE-100 (hydrochloride) also suppresses ER stress-induced hippocampal cell death[2].

For research use only. We do not sell to patients.

NE-100 hydrochloride Chemical Structure

NE-100 hydrochloride Chemical Structure

CAS No. : 149409-57-4

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1 mg USD 50 In-stock
5 mg USD 105 In-stock
10 mg USD 170 In-stock
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Based on 1 publication(s) in Google Scholar

NE-100 hydrochloride Related Antibodies

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Description

NE-100 (hydrochloride) is a potent and selective sigma-1 receptor antagonist with an IC50 of 4.16 nM. NE-100 (hydrochloride) exerts antipsychotic activity in vivo[1]. NE-100 (hydrochloride) also suppresses ER stress-induced hippocampal cell death[2].

Molecular Weight

391.97

Appearance

Solid

Formula

C23H34ClNO2
CAS No.
SMILES

CCCN(CCC)CCC1=CC=C(OC)C(OCCC2=CC=CC=C2)=C1.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (637.80 mM; Need ultrasonic)

H2O : ≥ 100 mg/mL (255.12 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5512 mL 12.7561 mL 25.5122 mL
5 mM 0.5102 mL 2.5512 mL 5.1024 mL
10 mM 0.2551 mL 1.2756 mL 2.5512 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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NE-100 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2

Keywords:

NE-100149409-57-4NE100NE 100Sigma ReceptorInhibitorinhibitorinhibit

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