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  3. STM2457

STM2457 

Cat. No.: HY-134836
Handling Instructions

STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor. STM2457 can be used for the research of acute myeloid leukaemia (AML).

For research use only. We do not sell to patients.

STM2457 Chemical Structure

STM2457 Chemical Structure

CAS No. : 2499663-01-1

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Description

STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor. STM2457 can be used for the research of acute myeloid leukaemia (AML)[1][2].

In Vitro

STM2457 (Compound 72) inhibits MOLM13 cells proliferation with an IC50 of 8.699 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

444.53

Formula

C₂₅H₂₈N₆O₂

CAS No.
SMILES

O=C(C(N=C1N2C=CC=C1)=CC2=O)NCC3=CN4C=C(CNCC5CCCCC5)C=CC4=N3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

STM2457STM 2457STM-2457Apoptosiscancermyeloidleukaemiaautoimmune diseasesInhibitorinhibitorinhibit

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