2499663-01-1
2499663-01-1
Chemical Structure
STM2457
- CAS. Nr.: 2499663-01-1
- Formula:C25H28N6O2
- Molecular Weight:444.53
IUPAC Name: N-((6-(((cyclohexylmethyl)amino)methyl)imidazo[1,2-a]pyridin-2-yl)methyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxamide
InChIKey: OBERVORNENYOLE-UHFFFAOYSA-N
SMILES: O=C(C(N=C1N2C=CC=C1)=CC2=O)NCC3=CN4C=C(CNCC5CCCCC5)C=CC4=N3
Biological Activity: STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor with an IC50 of 16.9 nM. STM2457 can be used for the research of acute myeloid leukaemia (AML)[1][2].
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STM2457 | 99.55% | STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor with an IC50 of 16.9 nM. STM2457 can be used for the research of acute myeloid leukaemia (AML). | ||||||||||||||||||||
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References
Keywords
