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Art. -Nr.: HY-134836R

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STM2457 (Standard)

STM2457 (Standard) is the analytical standard of STM2457 (HY-134836). This product is intended for research and analytical applications. STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor with an IC₅₀ of 16.9 nM. STM2457 can be used for the research of acute myeloid leukaemia (AML).

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2499663-01-1
Formel: C₂₅H₂₈N₆O₂
Molecular Weight:444.53

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

STM2457 (Standard) Chemical Structure

CAS. Nr.: 2499663-01-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
- Information
- Anwendung
Chemical Information
Reinheit & Dokumentation
Calculators
Help & FAQs
Classifications
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Product Information

Information

Anwendung

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS. Nr. 2499663-01-1
Molecular Weight 444.53
Formel C₂₅H₂₈N₆O₂
SMILES

O=C(C(N=C1N2C=CC=C1)=CC2=O)NCC3=CN4C=C(CNCC5CCCCC5)C=CC4=N3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Wesley Peter Blackaby, et al. Mettl3 inhibitory compounds. WO2020201773A1.

[2]. Eliza Yankova, et al. Small molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature. 2021 Apr 26. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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