2. Epigenetics
  3. METTL3
  4. STC-15

STC-15 (example 70) is an orally active METTL3 inhibitor used in the study of proliferative diseases such as cancer and autoimmune diseases.

For research use only. We do not sell to patients.

STC-15 Chemical Structure

STC-15 Chemical Structure

CAS No. : 2648257-56-9

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5 mg USD 580 In-stock
10 mg USD 920 In-stock
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Based on 1 publication(s) in Google Scholar

STC-15 Related Antibodies

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Description

STC-15 (example 70) is an orally active METTL3 inhibitor used in the study of proliferative diseases such as cancer and autoimmune diseases[1].

Molecular Weight

415.49

Formula

C24H25N5O2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1C=C(C(NCC2=CC3=C(C=C(CNCC4CCC4)N3)C=C2)=O)N=C5C=CC=CN15
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (300.85 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4068 mL 12.0340 mL 24.0680 mL
5 mM 0.4814 mL 2.4068 mL 4.8136 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4068 mL 12.0340 mL 24.0680 mL 60.1699 mL
5 mM 0.4814 mL 2.4068 mL 4.8136 mL 12.0340 mL
10 mM 0.2407 mL 1.2034 mL 2.4068 mL 6.0170 mL
15 mM 0.1605 mL 0.8023 mL 1.6045 mL 4.0113 mL
20 mM 0.1203 mL 0.6017 mL 1.2034 mL 3.0085 mL
25 mM 0.0963 mL 0.4814 mL 0.9627 mL 2.4068 mL
30 mM 0.0802 mL 0.4011 mL 0.8023 mL 2.0057 mL
40 mM 0.0602 mL 0.3008 mL 0.6017 mL 1.5042 mL
50 mM 0.0481 mL 0.2407 mL 0.4814 mL 1.2034 mL
60 mM 0.0401 mL 0.2006 mL 0.4011 mL 1.0028 mL
80 mM 0.0301 mL 0.1504 mL 0.3008 mL 0.7521 mL
100 mM 0.0241 mL 0.1203 mL 0.2407 mL 0.6017 mL
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STC-15 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STC-152648257-56-9STC15STC 15METTL3Methyltransferase-like 3cancerautoimmune diseasesInhibitorinhibitorinhibit

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