Pol I-IN-1
Pol I-IN-1 is a potent RNA polymerase I (Pol I) inhibitor with IC50 0.21 µM for the Pol I large catalytic subunit RPA194.
For research use only. We do not sell to patients.
- CAS No.: 2765318-69-0
- Formula: C23H22N4O2
- Molecular Weight:386.45
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All DNA/RNA Synthesis Isoforms
More
Biological Activity
|
RNA Polymerase |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-375 | IC50 |
38 nM
Compound: 31
|
Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer glo luminescent assay
Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer glo luminescent assay
|
[PMID: 35450366] |
Chemical Information
-
CAS No. 2765318-69-0
-
Molecular Weight 386.45
-
Formula C23H22N4O2
-
SMILES
O=C(C1=CC=CN2C(C3=C(C4=C(C=C3)C=CC=C4)N=C12)=O)NCCN5CCCC5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pol I-IN-1 Related Classifications
HY-145840 Related Classifications
Powered by Bioz