EGFR/CDK2-IN-3
EGFR/CDK2-IN-3 (compound 4b) is a dual inhibitor of EGFR and CDK-2 with IC50s of 71.7 and 113.7 nM, respectively. EGFR/CDK2-IN-3 induces apoptosis in MCF-7 cells and arrests the cell cycle in the S phase. EGFR/CDK2-IN-3 has significant anti-cancer cell toxicity and inhibits MCF-7 with an IC50 of 3.16 μM.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C30H20N6OS
- Peso molecular:512.58
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
IC50: 71.7 (EGFR), 113.7 nM (CDK-2)[1]
Chemical Information
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Peso molecular 512.58
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Fòrmula C30H20N6OS
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SMILES
O=C(C1=CN(C2=CC=CC=C2)N=C1C3=NN4C(SC3)=NN=C4C5=CC=CC=C5)C6=CC=C7C=CC=CC7=C6
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR/CDK2-IN-3 Related Classifications
HY-156115 Related Classifications
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