1. Metabolic Enzyme/Protease
  2. Tyrosinase
  3. Tyrosinase-IN-10

Tyrosinase-IN-10 (Compound 23) is a partially competitive tyrosinase inhibitor with an IC50 of 1.6 μM against tyrosinase activity from human melanoma cell lysates.

For research use only. We do not sell to patients.

Tyrosinase-IN-10 Chemical Structure

Tyrosinase-IN-10 Chemical Structure

CAS No. : 2873418-48-3

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Tyrosinase-IN-10 (Compound 23) is a partially competitive tyrosinase inhibitor with an IC50 of 1.6 μM against tyrosinase activity from human melanoma cell lysates[1].

IC50 & Target

IC50: 1.6 μM (human tyrosinase)[1]

In Vitro

Tyrosinase-IN-10 (Compound 23) (0-100 μM; 96 h) inhibits MNT-1 whole cells melanogenesis with an IC50 of 29 μM and shows cytotoxicity with a CC50 of 91 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: MNT-1 cells
Concentration: 0-100 μM
Incubation Time: 96 h
Result: Showed cytotoxicity with a CC50 of 91 μM.
Molecular Weight

268.26

Formula

C16H12O4

CAS No.
SMILES

O=C1C2=CC=CC(O)=C2C/C1=C\C3=C(C=C(C=C3)O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Tyrosinase-IN-10 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Tyrosinase-IN-10
Cat. No.:
HY-152194
Quantity:
MCE Japan Authorized Agent: