2. Protein Tyrosine Kinase/RTK
  3. FLT3
  4. FLT3-IN-16

FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia.

For research use only. We do not sell to patients.

FLT3-IN-16 Chemical Structure

FLT3-IN-16 Chemical Structure

CAS No. : 298207-49-5

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 165 In-stock
Solution
10 mM * 1 mL in DMSO USD 165 In-stock
Solid
5 mg USD 150 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
50 mg USD 850 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

FLT3-IN-16 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

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Description

FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].

IC50 & Target

IC50: 1.1 μM (FLT3)[1]
In Vitro

FLT3-IN-16 (compound 9, 0-10 μM) exhibits anti-proliferative activities against MV4-11 cells with an IC50 value of 2.0 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FLT3-IN-16 Related Antibodies
Molecular Weight

301.36

Formula

C15H15N3O2S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=C(NC(C2=CC=CN=C2)=O)SC3=C1CCCC3)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (82.96 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3183 mL 16.5915 mL 33.1829 mL
5 mM 0.6637 mL 3.3183 mL 6.6366 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3183 mL 16.5915 mL 33.1829 mL 82.9573 mL
5 mM 0.6637 mL 3.3183 mL 6.6366 mL 16.5915 mL
10 mM 0.3318 mL 1.6591 mL 3.3183 mL 8.2957 mL
15 mM 0.2212 mL 1.1061 mL 2.2122 mL 5.5305 mL
20 mM 0.1659 mL 0.8296 mL 1.6591 mL 4.1479 mL
25 mM 0.1327 mL 0.6637 mL 1.3273 mL 3.3183 mL
30 mM 0.1106 mL 0.5530 mL 1.1061 mL 2.7652 mL
40 mM 0.0830 mL 0.4148 mL 0.8296 mL 2.0739 mL
50 mM 0.0664 mL 0.3318 mL 0.6637 mL 1.6591 mL
60 mM 0.0553 mL 0.2765 mL 0.5530 mL 1.3826 mL
80 mM 0.0415 mL 0.2074 mL 0.4148 mL 1.0370 mL
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FLT3-IN-16 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FLT3-IN-16298207-49-5FLT3Cluster of differentiation antigen 135CD135Fms like tyrosine kinase 3acute myeloid leukemiaanti-proliferativeMV4-11 cellsInhibitorinhibitorinhibit

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