1. Anti-infection
  2. Bacterial
  3. PF-04753299

PF-04753299 

Cat. No.: HY-125789
Handling Instructions

PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection.

For research use only. We do not sell to patients.

PF-04753299 Chemical Structure

PF-04753299 Chemical Structure

CAS No. : 1289620-49-0

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Description

PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection[1].

IC50 & Target

IC50: bacterial[1]

Molecular Weight

347.43

Formula

C₁₈H₂₁NO₄S

CAS No.

1289620-49-0

SMILES

O=C(NO)[[email protected]@](S(=O)(C)=O)(C)CCC1=CC=C(C2=CC=CC=C2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

PF-04753299PF04753299PF 04753299BacterialLpxCK. pneumoniae E. coliP. aeruginosainfectionMDRgonococcalInhibitorinhibitorinhibit

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PF-04753299
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