1289620-49-0

PF-04753299 Chemical Structure
1289620-49-0

Chemical Structure

PF-04753299

  • CAS No.: 1289620-49-0
  • Formula:C18H21NO4S
  • Molecular Weight:347.43

IUPAC Name: (R)-4-([1,1'-biphenyl]-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide

InChIKey: GDYIQUFNICPYHF-GOSISDBHSA-N

SMILES: O=C(NO)[C@@](S(=O)(C)=O)(C)CCC1=CC=C(C2=CC=CC=C2)C=C1

Biological Activity: PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection[1].

Cat. No. Product Name Purity Description Pricing
HY-125789
PF-04753299 99.58% PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection.
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