1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. JP1302 dihydrochloride

JP1302 dihydrochloride 

Cat. No.: HY-103213
Handling Instructions

JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Kb value (antagonist activity) of 16 nM and a Ki (binding affinity) value of 28 nM.

For research use only. We do not sell to patients.

JP1302 dihydrochloride Chemical Structure

JP1302 dihydrochloride Chemical Structure

CAS No. : 1259314-65-2

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Description

JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Kb value (antagonist activity) of 16 nM and a Ki (binding affinity) value of 28 nM[1][2].

IC50 & Target

Ki: 28 nM (α2C- adrenoceptor)[2].
Kb: 16 nM (α2C- adrenoceptor)[2].

Molecular Weight

441.40

Formula

C₂₄H₂₆Cl₂N₄

CAS No.

1259314-65-2

SMILES

CN1CCN(C2=CC=C(NC3=C(C=CC=C4)C4=NC5=CC=CC=C53)C=C2)CC1.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
JP1302 dihydrochloride
Cat. No.:
HY-103213
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