2. JAK/STAT Signaling
  3. Pim
  4. FD1024

FD1024 is PIM inhibitor (IC50s: 1.96, 38.9, 4.17 nM for PIM1, 2, 3). FD1024 can be used for research of acute myeloid leukemia. FD1024 has strong antiproliferative activity against the tested AML cell lines, with 0.16 μM, 0.12 μM, 1.05 μM, 1.39μM for EOL-1, MV-4-11, KG-1, MOLM-16 cells. FD1024 also has antitumor efficacy in mice.

For research use only. We do not sell to patients.

FD1024 Chemical Structure

FD1024 Chemical Structure

CAS No. : 1422456-47-0

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FD1024 Related Antibodies

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Description

FD1024 is PIM inhibitor (IC50s: 1.96, 38.9, 4.17 nM for PIM1, 2, 3). FD1024 can be used for research of acute myeloid leukemia. FD1024 has strong antiproliferative activity against the tested AML cell lines, with 0.16 μM, 0.12 μM, 1.05 μM, 1.39μM for EOL-1, MV-4-11, KG-1, MOLM-16 cells. FD1024 also has antitumor efficacy in mice[1].

IC50 & Target

1.96, 38.9, 4.17 nM for PIM1, 2, 3[1]
Molecular Weight

430.47

Formula

C21H20F2N4O2S
CAS No.
SMILES

O=C(C1=CSC(C2=C(F)C=CC=C2F)=N1)NC3=C(O[C@H]4CC[C@H](N)CC4)C=CN=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FD1024 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FD10241422456-47-0FD 1024FD-1024PimPim kinasesAntiproliferativeacute myeloid leukemiaAMLEOL-1MV-4-11KG-1MOLM-16Inhibitorinhibitorinhibit

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