1. Membrane Transporter/Ion Channel
  2. Chloride Channel
  3. T16Ainh-A01

T16Ainh-A01 

Cat. No.: HY-100612
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T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).

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T16Ainh-A01 Chemical Structure

T16Ainh-A01 Chemical Structure

CAS No. : 552309-42-9

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Description

T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC)[1][2].

IC50 & Target

TMEM16A[1].

Molecular Weight

416.52

Formula

C₁₉H₂₀N₄O₃S₂

CAS No.

552309-42-9

SMILES

O=C(NC1=NC(C2=CC=C(OC)C=C2)=CS1)CSC3=NC(C)=C(CC)C(N3)=O

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T16Ainh-A01
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