Ac-hMCH(6-16)-NH2
Based on 1 Customer Validation
Ac-hMCH(6-16)-NH2 binds to and activates equally well both human MCH receptors present in the brain (non-selective agonist), with IC50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 353486-32-5
- Formula: C58H97N21O13S3
- Molecular Weight:1392.72
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Ac-hMCH(6-16)-NH2 exhibits EC50 values of 20 nM and 98 nM for MCH-1R and MCH-2R in aequorin functional assay, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 353486-32-5
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Appearance Solid
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Molecular Weight 1392.72
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Formula C58H97N21O13S3
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Color White to off-white
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Sequence
Ac-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-NH2 (disulfide bridge:Cys2-Cys11)
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Sequence Shortening
Ac-RCMLGRVYRPC-NH2 (disulfide bridge:Cys2-Cys11)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (71.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7180 mL | 3.5901 mL | 7.1802 mL | 17.9505 mL |
| 5 mM | 0.1436 mL | 0.7180 mL | 1.4360 mL | 3.5901 mL | |
| 10 mM | 0.0718 mL | 0.3590 mL | 0.7180 mL | 1.7950 mL | |
| 15 mM | 0.0479 mL | 0.2393 mL | 0.4787 mL | 1.1967 mL | |
| 20 mM | 0.0359 mL | 0.1795 mL | 0.3590 mL | 0.8975 mL | |
| 25 mM | 0.0287 mL | 0.1436 mL | 0.2872 mL | 0.7180 mL | |
| 30 mM | 0.0239 mL | 0.1197 mL | 0.2393 mL | 0.5983 mL | |
| 40 mM | 0.0180 mL | 0.0898 mL | 0.1795 mL | 0.4488 mL | |
| 50 mM | 0.0144 mL | 0.0718 mL | 0.1436 mL | 0.3590 mL | |
| 60 mM | 0.0120 mL | 0.0598 mL | 0.1197 mL | 0.2992 mL |