1. Protein Tyrosine Kinase/RTK
  2. c-Met/HGFR
  3. c-met-IN-1

c-met-IN-1 

Cat. No.: HY-101031
Handling Instructions

c-met-IN-1 (compound 16) is a potent and selective c-Met inhibitor, with IC50 of 1.1 nM, with antitumor activity..

For research use only. We do not sell to patients.

c-met-IN-1 Chemical Structure

c-met-IN-1 Chemical Structure

CAS No. : 2084836-84-8

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Description

c-met-IN-1 (compound 16) is a potent and selective c-Met inhibitor, with IC50 of 1.1 nM, with antitumor activity.[1].

IC50 & Target

IC50: 1.1 nM (c-Met)[1]

In Vitro

c-met-IN-1 (compound 16) exhibits high selectivity and remarkable cytotoxicity against HT-29, MKN-45 and A549 cells with IC50 values of 0.08 μM, 0.22 μM and 0.07 μM, respectively[1].

Molecular Weight

640.70

Formula

C₃₅H₃₇FN₆O₅

CAS No.

2084836-84-8

SMILES

FC1=CC(NC(C2=CN(C3=C(OC)C=CC=C3)C=N2)=O)=CC=C1OC4=CC=NC5=CC(OCCCN6CCN(C)CC6)=C(OC)C=C54

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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c-met-IN-1
Cat. No.:
HY-101031
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