2. Membrane Transporter/Ion Channel
  3. Chloride Channel
  4. Ani9

Ani9 is a potent and selective transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with IC50 at 77 nM. Ani9 can be applied to the study of cancer and other diseases.

For research use only. We do not sell to patients.

Ani9 Chemical Structure

Ani9 Chemical Structure

CAS No. : 356102-14-2

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Solid + Solvent
10 mM * 1 mL in DMSO
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10 mM * 1 mL in DMSO USD 105 In-stock
Solid
5 mg USD 95 In-stock
10 mg USD 165 In-stock
25 mg USD 345 In-stock
50 mg USD 580 In-stock
100 mg USD 980 In-stock
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Based on 1 publication(s) in Google Scholar

Ani9 Related Antibodies

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Description

Ani9 is a potent and selective transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with IC50 at 77 nM. Ani9 can be applied to the study of cancer and other diseases[1][2].

Molecular Weight

332.78

Formula

C17H17ClN2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(COC1=CC=C(C=C1C)Cl)N/N=C/C2=CC=CC=C2OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (375.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0050 mL 15.0249 mL 30.0499 mL
5 mM 0.6010 mL 3.0050 mL 6.0100 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0050 mL 15.0249 mL 30.0499 mL 75.1247 mL
5 mM 0.6010 mL 3.0050 mL 6.0100 mL 15.0249 mL
10 mM 0.3005 mL 1.5025 mL 3.0050 mL 7.5125 mL
15 mM 0.2003 mL 1.0017 mL 2.0033 mL 5.0083 mL
20 mM 0.1502 mL 0.7512 mL 1.5025 mL 3.7562 mL
25 mM 0.1202 mL 0.6010 mL 1.2020 mL 3.0050 mL
30 mM 0.1002 mL 0.5008 mL 1.0017 mL 2.5042 mL
40 mM 0.0751 mL 0.3756 mL 0.7512 mL 1.8781 mL
50 mM 0.0601 mL 0.3005 mL 0.6010 mL 1.5025 mL
60 mM 0.0501 mL 0.2504 mL 0.5008 mL 1.2521 mL
80 mM 0.0376 mL 0.1878 mL 0.3756 mL 0.9391 mL
100 mM 0.0300 mL 0.1502 mL 0.3005 mL 0.7512 mL
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Ani9 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ani9356102-14-2Ani 9Ani-9Chloride ChannelCl− ChannelsAnoctamin 1 (ANO1)InhibitorAnticancer agentinhibitorinhibit

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