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Cat. No.: HY-157612

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DHX9-IN-16

DHX9-IN-16 (208) is a RNA helicase DHX9 inhibitor, with an EC₅₀ of 0.125 μM in DHX9 cellular target engagement. Used in cancer research.

For research use only. We do not sell to patients.

CAS No.: 2973397-48-5
Formula: C₁₉H₂₀ClN₅O₄S
Molecular Weight:449.91

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

DHX9-IN-16 Chemical Structure

CAS No.: 2973397-48-5

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Sample (0.1mg)

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(In Japan)

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

DHX9-IN-16 (208) is a RNA helicase DHX9 inhibitor, with an EC₅₀ of 0.125 μM in DHX9 cellular target engagement. Used in cancer research^[1].

IC₅₀ & Target

Helicase

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 2973397-48-5
Molecular Weight 449.91
Formula C₁₉H₂₀ClN₅O₄S
SMILES

O=C(C1=CN(C2=NC=C(C=N2)OCC)C(C)=C1)NC3=CC(Cl)=CC(NS(=O)(C)=O)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Matthew H, et al.Matthew H, et al. Inhibitors of rna helicase dhx9 and uses thereof. Patent WO2023154519. Inhibitors of rna helicase dhx9 and uses thereof. Patent WO2023154519.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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