1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Cadherins
  5. LI-Cadherin/Cadherin-17
  6. Cadherin-17 Protein, Human (765a.a, HEK293, hFc)

Cadherin-17 Protein, Human (765a.a, HEK293, hFc)

Cat. No.: HY-P700688
Handling Instructions

Cadherin-17 protein mediates cell-cell interactions, sorting and organizing heterogeneous cell types by preferentially binding to other Cadherin-17 molecules. LI-cadherin, a subtype of Cadherin-17, is implicated in liver and intestinal morphological organization. Cadherin-17 also facilitates intestinal peptide transport, emphasizing its functional significance. Cadherin-17 Protein, Human (765a.a, HEK293, hFc) is the recombinant human-derived Cadherin-17 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-17 Protein, Human (765a.a, HEK293, hFc) is 765 a.a., with molecular weight of 113-135 kDa.

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Description

Cadherin-17 protein mediates cell-cell interactions, sorting and organizing heterogeneous cell types by preferentially binding to other Cadherin-17 molecules. LI-cadherin, a subtype of Cadherin-17, is implicated in liver and intestinal morphological organization. Cadherin-17 also facilitates intestinal peptide transport, emphasizing its functional significance. Cadherin-17 Protein, Human (765a.a, HEK293, hFc) is the recombinant human-derived Cadherin-17 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-17 Protein, Human (765a.a, HEK293, hFc) is 765 a.a., with molecular weight of 113-135 kDa.

Background

Cadherin-17 protein, a calcium-dependent cell adhesion molecule, is involved in mediating cell-cell interactions. Through its preferential homophilic interaction with other cadherin molecules of the same type in connecting cells, Cadherin-17 contributes to the sorting and organization of heterogeneous cell types. Specifically, LI-cadherin, a subtype of Cadherin-17, may play a role in the morphological organization of the liver and intestine. Furthermore, Cadherin-17 is involved in facilitating intestinal peptide transport, highlighting its functional significance in cellular processes.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

Q12864 (Q23-M787)

Gene ID
Molecular Construction
N-term
Cadherin-17 (Q23-M787)
Accession # Q12864
hFc
C-term
Synonyms
Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024
Molecular Weight

113-135 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Cadherin-17 Protein, Human (765a.a, HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Cadherin-17 Protein, Human (765a.a, HEK293, hFc)
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HY-P700688
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