Antiproliferative agent-35
Antiproliferative agent-35 (Compound 4) is an anticancer agent derivated from Esculetin (HY-N0284). Antiproliferative agent-35 inhibits the proliferation of B16 and A549 cells, with IC50s of 13.2 and 9.2 μM resspectively.
For research use only. We do not sell to patients.
- CAS No.: 82747-36-2
- Formula: C10H5F3O4
- Molecular Weight:246.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.0025 μM
Compound: 4
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Potentiation of taxol-induced cytotoxicity against human A549 cells assessed as taxol IC50 for inhibition of cell viability measured after 48 hrs by SRB assay (Rvb = 0.034 microM)
Potentiation of taxol-induced cytotoxicity against human A549 cells assessed as taxol IC50 for inhibition of cell viability measured after 48 hrs by SRB assay (Rvb = 0.034 microM)
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[PMID: 33218896] |
Chemical Information
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CAS No. 82747-36-2
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Molecular Weight 246.14
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Formula C10H5F3O4
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SMILES
C1=C2C(=CC(=O)OC2=CC(=C1O)O)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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