CCR8 antagonist 1
Based on 1 Customer Validation
CCR8 antagonist 1 (Compound 15) is a potente human CCR8 antagonist with a Ki of 1.6 nM. CCR8 antagonist 1 has high safety and metabolic stability. CCR8 antagonist 1 can be used to study diseases such as asthma and multiple sclerosis.
For research use only. We do not sell to patients.
- Purity: 99.50%
- CAS No.: 723304-76-5
- Formula: C26H29N3O5S
- Molecular Weight:495.59
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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CCR8 1.6 nM (Ki) |
Chemical Information
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CAS No. 723304-76-5
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Appearance Solid
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Molecular Weight 495.59
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Formula C26H29N3O5S
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Color White to off-white
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SMILES
O=C(N1CCC(NS(=O)(C2=C3C=CC=CC3=C(NC(C4=CC=CC=C4C)=O)C=C2)=O)CC1)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (50.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0178 mL | 10.0890 mL | 20.1780 mL | 50.4449 mL |
| 5 mM | 0.4036 mL | 2.0178 mL | 4.0356 mL | 10.0890 mL | |
| 10 mM | 0.2018 mL | 1.0089 mL | 2.0178 mL | 5.0445 mL | |
| 15 mM | 0.1345 mL | 0.6726 mL | 1.3452 mL | 3.3630 mL | |
| 20 mM | 0.1009 mL | 0.5044 mL | 1.0089 mL | 2.5222 mL | |
| 25 mM | 0.0807 mL | 0.4036 mL | 0.8071 mL | 2.0178 mL | |
| 30 mM | 0.0673 mL | 0.3363 mL | 0.6726 mL | 1.6815 mL | |
| 40 mM | 0.0504 mL | 0.2522 mL | 0.5044 mL | 1.2611 mL | |
| 50 mM | 0.0404 mL | 0.2018 mL | 0.4036 mL | 1.0089 mL |
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