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F16 

Cat. No.: HY-100395 Purity: >98.0%
Data Sheet SDS Handling Instructions

F16 is a small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines.

For research use only. We do not sell to patients.
F16 Chemical Structure

F16 Chemical Structure

CAS No. : 36098-33-6

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $55 In-stock
10 mg $50 In-stock
25 mg $100 In-stock
50 mg $180 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Description

F16 is a small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines. 1, F16 induced cell cycle arrest in sensitive mouse tumor and human cancer cell lines. 2, Prolonged incubation with 3 uM F16 resulted in increased cell death of F16-sensitive cells but not of F16-resistant ones. 3, F16 caused apoptosis in A6 cells. 4, F16 caused a dramatic decrease in the number of cells in S phase and an increase in the percentage of cells in G1 phase. 5, F16 is capable of inhibiting oxidative phosphorylation and inducing mitochondrial transmembrane depolarization.

References
Molecular Weight

362.21

Formula

C₁₆H₁₅IN₂

CAS No.

36098-33-6

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 31 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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F16
Cat. No.:
HY-100395
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